Issue 19, 2005
From the journal:

Organic & Biomolecular Chemistry

Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics

Tamas Kálai,a   Govindasamy Mugesh,b   Gouriprasanna Roy,b   Helmut Sies,c   Zoltán Berented  and  Kálmán Hideg*a  

* Corresponding authors

a Institute of Organic and Medicinal Chemistry, University of Pécs, P. O. Box 99, H-7602, Pécs, Hungary
E-mail: kalman.hideg@aok.pte.hu
Fax: +36-72-536219
Tel: +36-72-536221

b Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, India

c Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Postfach 101007, Düsseldorf, Germany

d Institute of Biochemistry and Medical Chemistry, University of Pécs, P. O. Box 99, Pécs, Hungary

Abstract

Benzo[d]isoselenazol-3-ones N-substituted with sterically hindered diamagnetic and paramagnetic five- or six-membered nitroxides or their precursors, including ring-opened diselenides, exhibit synergism in glutathione peroxidase (GPx) activity.

Graphical abstract: Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B509865C
Article type
Paper
Submitted
13 Jul 2005
Accepted
08 Aug 2005
First published
31 Aug 2005

Org. Biomol. Chem., 2005,3, 3564-3569

Permissions

Request permissions

Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics

T. Kálai, G. Mugesh, G. Roy, H. Sies, Z. Berente and K. Hideg, Org. Biomol. Chem., 2005, 3, 3564 DOI: 10.1039/B509865C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements