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Issue 19, 2005
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Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics

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Abstract

Benzo[d]isoselenazol-3-ones N-substituted with sterically hindered diamagnetic and paramagnetic five- or six-membered nitroxides or their precursors, including ring-opened diselenides, exhibit synergism in glutathione peroxidase (GPx) activity.

Graphical abstract: Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics

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Publication details

The article was received on 13 Jul 2005, accepted on 08 Aug 2005 and first published on 31 Aug 2005


Article type: Paper
DOI: 10.1039/B509865C
Citation: Org. Biomol. Chem., 2005,3, 3564-3569
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    Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics

    T. Kálai, G. Mugesh, G. Roy, H. Sies, Z. Berente and K. Hideg, Org. Biomol. Chem., 2005, 3, 3564
    DOI: 10.1039/B509865C

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