Issue 1, 2005
From the journal:

Organic & Biomolecular Chemistry

Synthesis and hetero-Michael addition reactions of 2-alkynyl oxazoles and oxazolines†

Peter Wipf*a  and  Thomas H. Grahama  

* Corresponding authors

a Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
E-mail: pwipf@pitt.edu
Fax: +1-412-624-0787
Tel: +1-412-624-8606

Abstract

Stereoselective conjugate additions of alcohols, amines, thiols, and halides to C(2)-alkynyl oxazoles and oxazolines provide a versatile entry to heterocyclic building blocks.

Graphical abstract: Synthesis and hetero-Michael addition reactions of 2-alkynyl oxazoles and oxazolines

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Article information

DOI
https://doi.org/10.1039/B413604G
Article type
Communication
Submitted
06 Sep 2004
Accepted
10 Nov 2004
First published
25 Nov 2004

Org. Biomol. Chem., 2005,3, 31-35

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Synthesis and hetero-Michael addition reactions of 2-alkynyl oxazoles and oxazolines

P. Wipf and T. H. Graham, Org. Biomol. Chem., 2005, 3, 31 DOI: 10.1039/B413604G

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