Issue 1, 2005
From the journal:

Organic & Biomolecular Chemistry

Detection of single base mismatches and abasic sites using phenanthridinium as an artificial DNA base and charge donor†

Linda Valis,a   Nicole Amanna  and  Hans-Achim Wagenknecht*a  

* Corresponding authors

a Technical University Munich, Chemistry Department, Lichtenbergstr. 4, Garching, Germany
E-mail: Wagenknecht@ch.tum.de
Fax: 49 89 289-13210
Tel: 49 89 289-13303

Abstract

Combining the fluorescence properties of phenanthridinium as an artificial DNA base together with DNA-mediated charge transfer processes allows the homogeneous detection of DNA base mismatches and abasic sites.

Graphical abstract: Detection of single base mismatches and abasic sites using phenanthridinium as an artificial DNA base and charge donor

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Article information

DOI
https://doi.org/10.1039/B414672G
Article type
Communication
Submitted
22 Sep 2004
Accepted
28 Oct 2004
First published
18 Nov 2004

Org. Biomol. Chem., 2005,3, 36-38

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Detection of single base mismatches and abasic sites using phenanthridinium as an artificial DNA base and charge donor

L. Valis, N. Amann and H. Wagenknecht, Org. Biomol. Chem., 2005, 3, 36 DOI: 10.1039/B414672G

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