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Issue 1, 2005
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Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions

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Abstract

Tetrazole and acylsulfonamide organocatalysts derived from proline have been synthesised and applied to the asymmetric Mannich, nitro-Michael and aldol reactions to give results that are superior to the proline-catalysed counterpart.

Graphical abstract: Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions

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Publication details

The article was received on 24 Sep 2004, accepted on 05 Nov 2004 and first published on 29 Nov 2004


Article type: Paper
DOI: 10.1039/B414742A
Org. Biomol. Chem., 2005,3, 84-96

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    Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions

    A. J. A. Cobb, D. M. Shaw, D. A. Longbottom, J. B. Gold and S. V. Ley, Org. Biomol. Chem., 2005, 3, 84
    DOI: 10.1039/B414742A

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