Issue 1, 2005
From the journal:

Organic & Biomolecular Chemistry

Application of tandem Ugi multi-component reaction/ring closing metathesis to the synthesis of a conformationally restricted cyclic pentapeptide

Silvia Anthoine Dietrich,a   Luca Banfi,*a   Andrea Basso,a   Gianluca Damonte,b   Giuseppe Guantia  and  Renata Rivaa  

* Corresponding authors

a Department of Chemistry and Industrial Chemistry, via Dodecaneso 31, Genova, Italy
E-mail: banfi@chimica.unige.it
Fax: +390103536118
Tel: +390103536119

b Department of Experimental Medicine, Biochemistry Section, c/o Center of Excellence for Biomedical Research, University of Genova, v. le Benedetto XV, Genova, Italy

Abstract

A conformationally restricted cyclic pentapeptide, containing an unsaturated 9-membered lactam as a semi-rigid scaffold, was prepared in a very convergent manner, through tandem Ugi reaction/ring closing metathesis.

Graphical abstract: Application of tandem Ugi multi-component reaction/ring closing metathesis to the synthesis of a conformationally restricted cyclic pentapeptide

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Article information

DOI
https://doi.org/10.1039/B414374D
Article type
Paper
Submitted
17 Sep 2004
Accepted
19 Oct 2004
First published
23 Nov 2004

Org. Biomol. Chem., 2005,3, 97-106

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Application of tandem Ugi multi-component reaction/ring closing metathesis to the synthesis of a conformationally restricted cyclic pentapeptide

S. Anthoine Dietrich, L. Banfi, A. Basso, G. Damonte, G. Guanti and R. Riva, Org. Biomol. Chem., 2005, 3, 97 DOI: 10.1039/B414374D

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