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Issue 12, 2004
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Synthesis and application in asymmetric C–C bond formation of solution phase ligand libraries of monodentate phosphoramidites

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Abstract

A library of 96 unique monodentate phosphoramidite ligands has been synthesized in solution and used in the asymmetric conjugate addition of potassium vinyltrifluoroborate to enones resulting in up to 88% ee.

Graphical abstract: Synthesis and application in asymmetric C–C bond formation of solution phase ligand libraries of monodentate phosphoramidites

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Publication details

The article was received on 02 Apr 2004, accepted on 12 May 2004 and first published on 25 May 2004


Article type: Communication
DOI: 10.1039/B404996A
Org. Biomol. Chem., 2004,2, 1682-1684

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    Synthesis and application in asymmetric C–C bond formation of solution phase ligand libraries of monodentate phosphoramidites

    A. Duursma, L. Lefort, J. A. F. Boogers, A. H. M. de Vries, J. G. de Vries, A. J. Minnaard and B. L. Feringa, Org. Biomol. Chem., 2004, 2, 1682
    DOI: 10.1039/B404996A

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