Synthesis of 5-arylpyrrolo[1,2-c]pyrimidin-1(2H)-ones
Abstract
The preparation of several 2-substituted 5-arylpyrrolo[1,2-c]pyrimidinones 6 is described via palladium(0)-catalyzed couplings using 5-trimethylstannylpyrrolopyrimidinones 3.
* Corresponding authors
a Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, 08028 Barcelona, Spain
b Chemistry Department, The University of Manchester, Manchester, UK
The preparation of several 2-substituted 5-arylpyrrolo[1,2-c]pyrimidinones 6 is described via palladium(0)-catalyzed couplings using 5-trimethylstannylpyrrolopyrimidinones 3.
M. Álvarez, D. Fernández and J. A. Joule, J. Chem. Soc., Perkin Trans. 1, 2002, 471 DOI: 10.1039/B111142F
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