In vitro selection and evaluation of rna aptamers that recognize arginine-rich-motif model peptide on a quartz-crystal microbalance
Abstract
To study RNA–peptide interactions, we performed an in vitro selection of RNA on a simple α-helical peptide-immobilized quartz-crystal microbalance (QCM) and evaluated the association constants (107 M−1) of the selected RNA to the model peptide on the same QCM plate.