Respective conversion of n-butylamine to methyl N-n-butylcarbamate and oxalbutyline in supercritical carbon dioxide
Abstract
O2 and the solvent (MeOH–supercritical carbon dioxide) can control the chemoselectivity of the palladium-catalyzed carbonylation of amines; methyl N-n-butylcarbamate or oxalbutyline could be obtained in high yields upon varying the conditions.