Nickel-catalyzed cocyclotrimerization of oxa- and azabenzonorbornadienes with alkynes: reaction with multiple synthetic applications
Abstract
Oxa- and azabenzonorbornadienes react with alkynes in the presence of nickel complexes to give the corresponding [2+2+2] cycloadducts; these reactions can be applied to the construction of multiple fused rings, the preparation of precursors of isobenzofurans and isoindoles and aromatic compounds.