The Effect of Allylic Methoxyl Groups on the Hydroboration of a Steroidal Alkene
Abstract
The hydroboration of 3α-, 3β-, 6α- and 6β-methoxyandrost-4-enes has been shown to proceed predominantly trans to the methoxy group with, in the case of the 6-methoxy compounds, some Markownikoff hydration to form the tertiary C-5 alcohols, thus parallelling results obtained with the corresponding alcohols.