Issue 4, 1997

Synthesis and NMR studies of key intermediates to a new class of β-lactam: the trinems

Abstract

An efficient synthesis of the four isomeric epoxides 4a–d, key compounds to the trinem ring system, starting from (3R,4R,1′R)-(+)-4-acetoxy-3-[1′- (tert-butyldimethylsilyloxy)ethyl]azetidin-2-one 6a is described. All the intermediates have been characterized by means of NMR techniques.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1997, 463-468

Synthesis and NMR studies of key intermediates to a new class of β-lactam: the trinems

C. Marchioro, G. Pentassuglia, A. Perboni and D. Donati, J. Chem. Soc., Perkin Trans. 1, 1997, 463 DOI: 10.1039/A605081F

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