Issue 4, 1997

Fluoride ion-induced cyclization of o-[bis(trimethylsilyl)methyl]-N-acylbenzamide derivatives. New efficient synthesis of 2,3-differentially substituted 1(2H)-isoquinolones

Abstract

A wide variety of 2-alkyl-3-alkyl, -3-aryl and -3-heteroaryl-1(2H)-isoquinolones have been obtained by fluoride ion-induced intramolecular alkenation of o-[bis(trimethylsilyl)methyl]-N -acylbenzamide derivatives.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1997, 469-476

Fluoride ion-induced cyclization of o-[bis(trimethylsilyl)methyl]-N-acylbenzamide derivatives. New efficient synthesis of 2,3-differentially substituted 1(2H)-isoquinolones

A. Couture, H. Cornet, E. Deniau, P. Grandclaudon and S. Lebrun, J. Chem. Soc., Perkin Trans. 1, 1997, 469 DOI: 10.1039/A605077H

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