Acyl transfer reactions in dipolar aprotic medium: desolvated phosphate ion as acyl acceptor in the formation of energy-rich phosphate compounds

Abstract

The reaction between an acetate ester and n-decylphosphate ions in dipolar aprotic medium provides a system which allows the facile formation of acetyl phosphate derivatives, by means of restricting the quantities of water available in the reacting system; the role of water is explained in terms of the inhibition of the nucleophilic attack of the phosphate group, which is disfavoured by its presence.