A hammerhead ribozyme domain incorporating (–)-carbodine 8a and (–)-aristeromycin 8b at selected positions, manifests increased RNase resistance and exhibits significant catalytic activity.
F. Burlina, A. Favre, J. Fourrey and M. Thomas, Chem. Commun., 1996, 1623 DOI: 10.1039/CC9960001623
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