Issue 1, 1996

A novel [3 + 2] annulation: synthesis and X-ray crystallographic structure of a novel tetrahydropyrazolo[1,5-a] quinoline, an intermediate towards new tricyclic quinolone antibacterials

Abstract

The synthesis and X-ray crystallographic structure of tetrahydropyrazolo[1,5-a]quinoline 10, an intermediate for novel DNA gyrase inhibitors, via a tandem 1,4-conjugate addition-Michael ring closure protocol are described.

Article information

Article type
Paper

Chem. Commun., 1996, 61-62

A novel [3 + 2] annulation: synthesis and X-ray crystallographic structure of a novel tetrahydropyrazolo[1,5-a] quinoline, an intermediate towards new tricyclic quinolone antibacterials

D. Barrett, H. Sasaki, T. Kinoshita and K. Sakane, Chem. Commun., 1996, 61 DOI: 10.1039/CC9960000061

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