A novel [3 + 2] annulation: synthesis and X-ray crystallographic structure of a novel tetrahydropyrazolo[1,5-a] quinoline, an intermediate towards new tricyclic quinolone antibacterials
Abstract
The synthesis and X-ray crystallographic structure of tetrahydropyrazolo[1,5-a]quinoline 10, an intermediate for novel DNA gyrase inhibitors, via a tandem 1,4-conjugate addition-Michael ring closure protocol are described.
 
                



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