Issue 13, 1995

Oxidation of methyl p-tolyl sulfide with bakers' yeast: preparation of a synthon of the mevinic acid-type hypocholestemic agents

Abstract

Bakers' yeast oxidized methyl p-tolyl sulfide to produce the R-sulfoxide 1 in good yield and high enantiomeric excess; the sulfoxide 1 was used to prepare (4R,6S)-tert-butyldimethylsilyloxy-6-hydroxymethyltetrahydropyran-2-one 15.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1995, 1641-1643

Oxidation of methyl p-tolyl sulfide with bakers' yeast: preparation of a synthon of the mevinic acid-type hypocholestemic agents

J. Beecher, I. Brackenridge, S. M. Roberts, J. Tang and A. J. Willetts, J. Chem. Soc., Perkin Trans. 1, 1995, 1641 DOI: 10.1039/P19950001641

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