Synthesis of a new class of asymmetric ketone reduction catalyst via a diastereoselective cyclisation reaction: X-ray crystal structure of S(p)R-(–)-N-(tert-butyldiphenylsilyl)dihydrobenzazaphosphole oxide
Abstract
A stereoselective synthesis and X-ray crystal structure of dihydrobenzazaphosphole oxide S(p)R-trans-8, a precursor of a new class of asymmetric ketone reduction catalyst, is described.