Intramolecular Friedel–Crafts acylation of a pyrrole derived from L-glutamic acid, followed by a highly selective hydrogenation, leads to either of the optically pure indolizidine alkaloid precursors 6 or 7, depending on the catalyst.
T. J. Bond, R. Jenkins, A. C. Ridley and P. C. Taylor, J. Chem. Soc., Perkin Trans. 1, 1993, 2241 DOI: 10.1039/P19930002241
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