Synthesis of optically active 5′-noraristeromycin: enzyme-catalysed kinetic resolution of 9-(4-hydroxycyclopent-2-enyl)purines
Abstract
A facile chemo-enzymatic route to optically active 5′-noraristeromycin from the epoxide 2 employs an enantioselective Pseudomonas cepacia lipase-catalysed acetylation