Cycloaddition of diethylphosphonomethyl nitrile oxide to the enamine from ethyl acetoacetate produces 4-ethoxycarbonyl-3-diethoxyphosphonylmethyl-5-methylisoxazole; condensation of the phosphonate with aldehydes and ketones gives 3-alkenylisoxazoles that are cleaved by hexacarbonylmolybdenum to afford unsaturated α-alkoxycarbonyl-β-diketones.
R. C. F. Jones, G. Bhalay and P. A. Carter, J. Chem. Soc., Perkin Trans. 1, 1993, 1715 DOI: 10.1039/P19930001715
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