Rearrangement of 1,3-bis(azacrown)-2-chloropropanes: the effect of alkali metal ion on neighbouring group participation
Abstract
A pronounced effect of alkali metal ion on rate and product distribution has been found in the reaction of the twelve-, fifteen- and eighteen-membered 1,3-bis(azacrown)-2-chloropropanes 1a–c with benzyl oxide–benzyl alcohol base–solvent system.