Baker's yeast catalyses asymmetric cycloaddition of the benzonitrile N-oxides 2–4 to N-vinylcarbazole 1 to yield optically active 4,5-dihydroisoxazoles 5–7 in good yields with an enantiomeric excess (ee) of up to 51%.
K. R. Rao, Y. V. D. Nageswar and H. M. Sampathkumar, J. Chem. Soc., Perkin Trans. 1, 1990, 3199 DOI: 10.1039/P19900003199
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