Issue 8, 1990

Enantioselective synthesis of monofluorinated chiral building blocks from malonic acid

Abstract

A general method for the preparation of monofluorinated chiral building blocks has been developed by fluorination of methyl phenylmenthyl monoalkylmalonates using lithium hexamethyldisilazide and 1-fluoro-2,4,6-trimethylpyridinium triflate.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1990, 2357-2358

Enantioselective synthesis of monofluorinated chiral building blocks from malonic acid

M. Ihara, T. Kai, N. Taniguchi and K. Fukumoto, J. Chem. Soc., Perkin Trans. 1, 1990, 2357 DOI: 10.1039/P19900002357

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