Issue 4, 1990

A new synthesis of methyl α-acetolactate based on thiazolium chemistry and modelled on the enzymatic synthesis of α-acetolactate catalysed by acetolactate synthase

Abstract

Methyl α-acetolactate [methyl 2-hydroxy-2-methyl-3-oxobutanoate (13)] has been synthesised via a series of adducts with benzothiazole in a manner analogous to the enzymatic reaction catalysed by acetolactate synthase.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1990, 331-333

A new synthesis of methyl α-acetolactate based on thiazolium chemistry and modelled on the enzymatic synthesis of α-acetolactate catalysed by acetolactate synthase

D. H. G. Crout, E. R. Lee and D. P. J. Pearson, J. Chem. Soc., Chem. Commun., 1990, 331 DOI: 10.1039/C39900000331

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