Microbial resolution and asymmetric oxidation related to optically active 1,2-bis(methoxyphenyl)ethane-1,2-diol

Abstract

An efficient microbial resolution of 1,2-bis-(methoxyphenyl)ethane-1,2-diol (2) has been achieved by exposing the corresponding diacetate to Trichoderma viride(T. konigii); stereoselective epoxidation of allylic alcohols and oxidation of sulphides are achieved with Bu^tOOH using Ti(OPrⁱ)₄–optically active diols (2) as chiral catalysts.