Issue 4, 1988

Biotransformation in organic synthesis: applications of yeast reduction in the synthesis of 3,5-dihydroxy esters of high optical purity

Abstract

All four stereoisomers of methyl 6-(p-chlorophenylthio)-3,5-dihydroxyhexanoate have been synthesised by a route in which the key introduction of chirality was effected by an appropriate yeast reduction.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1988, 264-266

Biotransformation in organic synthesis: applications of yeast reduction in the synthesis of 3,5-dihydroxy esters of high optical purity

M. Christen and D. H. G. Crout, J. Chem. Soc., Chem. Commun., 1988, 264 DOI: 10.1039/C39880000264

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