The chiral vinyl sulphoximides (3a) and (3b) upon treatment with base, undergo cyclization to give chiral isoquinolines which were converted in to (R)-(+) and (S)-(–)-Carnegine.
S. G. Pyne, J. Chem. Soc., Chem. Commun., 1986, 1686 DOI: 10.1039/C39860001686
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