3,4-Disubstituted-1-arylazetidin-2-ones can be prepared in an enantiospecific manner by the annelation of Schiff bases from optically active glyceraldehyde acetonide and their stereochemistry determined from n.m.r. studies on lactones prepared from these β-lactams by molecular rearrangement.
A. K. Bose, V. R. Hegde, D. R. Wagle, S. S. Bari and M. S. Manhas, J. Chem. Soc., Chem. Commun., 1986, 161 DOI: 10.1039/C39860000161
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