Asymmetric Diels–Alder reactions of sulphinyl-activated dienophiles obtained via a self-induced chiral oxidation
Abstract
The Diels–Alder cycloaddition of activated vinyl sulphoxides (1), that are readily obtained by a self-induced chiral oxidation, proceeds highly diastereoselectively to form the corresponding cycloadducts (4) that can be converted into 2-substituted norbornadienes(5) of high enantiomeric purity.