The C-21 hydroxy group of C-17 and C-21 deuterium labelled tetrahydrooxycorticosterone is removed by the anaerobic bacteria Eubacterium lentum with retention of deuterium label at C-17α and loss of one of the two deuterium atoms originally present at C-21.
H. L. Holland and E. Riemland, J. Chem. Soc., Chem. Commun., 1984, 1481 DOI: 10.1039/C39840001481
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