The preparation and dienone–phenol rearrangement of androsta-2,5-diene-4,17-dione
Abstract
The preparation of androsta-2,5-diene-4,17-dione from dehydroisoandrosterone is described. Its dienone–phenol rearrangement, in the presence of hydrobromic acid and glacial acetic acid, affords 1-methyl-4-hydroxyestra-1,3,5(10)-trin-17-one.