The participation of 3,5-cyclosteroids in aromatization reactions
Abstract
The preparation of 6β,7β-dihydroxy-3α,5-cycloandrostan-17-one and 2β,17β-diacetoxy-6α-hydroxy-3α,5-cycloandrostane and their reaction with hydrobromic acid in acetic acid is described. They both afford the corresponding 4-methylestratriene accompanied by, in the case of the former, an anthrasteroid and in the case of the latter. 17β-acetoxy-5α-androst-2-en-6-one and the related 2- and 3-bromo-6-ones.