Raman optical activity due to isotopic substitution: (1S)-4,4-dideuterioadamantan-2-one

Abstract

Observations of Raman optical activity in CH₂ and CD₂ deformation modes of (1S)-4,4-dideuterioadamantan-2-one reinforce the expectation that vibrational optical activity measurements will become a powerful new means of studying the stereochemistry of molecules that owe their chirality to isotopic substitution.