Reaction of 6-amino-1,3-dimethyl-5-nitrosouracil with thiols
Abstract
The reactions of 6-amino-1,3-dimethyl-5-nitrosouracil with various thiols lead to condensation as well as oxidation–reduction products. Disulphides, 4,6-dimethyl[1,2,5]thiadiazolo[3,4-d]pyrimidine-5,7-dione, pteridine-2,4-diones, purine-2,6-diones, pyrimidopteridines, and 5,6-diamino-1,3-dimethyluracil were among those isolated. The mechanism of the reaction is discussed.