Absolute configuration of 3-aryloxypropane-1,2-diols and derivatives: mephenesin isomers
Abstract
The optical isomers of mephenesin (3-o-tolylpropane-1,2-diol) were prepared from 2R- and 2S-3-tosyloxypropane-1,2-diol acetonide by reaction with o-cresol(NaOH) and the configurations confirmed on the basis of c.d. spectra in Cupra A Solution.