Issue 7, 1972

Nucleophilic substitution reactions of allylic halides carrying electron-withdrawing substituents in the γ-position. Formation of cyclopropanes from dimethyl 2-bromo-2-methylpropylidenemalonate

Abstract

Reaction of dimethyl 2-bromo-2-methylpropylidenemalonate with sodium methoxide or potassium cyanide in methanol produces cyclopropane derivatives in high yields, thus indicating an overall substitution with nucleophilic attack occurring at the β-position of the allylic halide.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1972, 375-375

Nucleophilic substitution reactions of allylic halides carrying electron-withdrawing substituents in the γ-position. Formation of cyclopropanes from dimethyl 2-bromo-2-methylpropylidenemalonate

P. Kolsaker and H. J. Storesund, J. Chem. Soc., Chem. Commun., 1972, 375 DOI: 10.1039/C39720000375

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