Relative stereochemistry of protonation and hydroxylation in the biosynthesis of lycorenine and haemanthidine from protocatechualdehyde
Abstract
Tracer experiments show that in the biosynthesis of lycorenine and haemanthidine the hydrogen introduced in the incorporation of protocatechualdehyde into the aromatic C6–C1 unit of O-methylnorbelladine is the one removed in the hydroxylation.