On the synthesis of 3-benzylidenepiperazine-2,5-diones
Abstract
Treatment of N-(chloroacetyl)phenylalanine with methylamine gives 3-trans-benzylidene-1-methylpiperazine 2,5-dione, also produced, with no acetyl group at position 4, by cyclisation of (N-acetyldehydrophenylalanyl)-sarcosine with acetic anhydride.