Issue 20, 1970

Enhanced reactivity of nucleophiles: the “α-effect” in reactions of benzyl bromide

Abstract

Benzyl bromide reacts rapidly with amidoximes in the neutral form by intramolecular base catalysis, and N-methylhydroxmic acids also show enhanced reactivity, attributed in this case to lone-pair repulsion.

Article information

Article type
Paper

J. Chem. Soc. D, 1970, 1378-1379

Enhanced reactivity of nucleophiles: the “α-effect” in reactions of benzyl bromide

J. D. Aubort and R. F. Hudson, J. Chem. Soc. D, 1970, 1378 DOI: 10.1039/C29700001378

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