Issue 7, 1969

1,2,3,4,6-Penta-azaindenes (8-azapurines). Part VI. Methylation of 8-azapurine

Abstract

A practicable methylation of 8-azapurine is described which gives 7-, 8-, and 9-methyl-8-azapurine in approximately equal amounts. After solvent extraction (from aqueous acid), which took advantage of the lower basic strength of the 9-isomer, t.l.c. was used to complete the separation of the isomers. Some alternative procedures are discussed.

Article information

Article type
Paper

J. Chem. Soc. C, 1969, 1084-1085

1,2,3,4,6-Penta-azaindenes (8-azapurines). Part VI. Methylation of 8-azapurine

A. Albert, W. Pfleiderer and D. Thacker, J. Chem. Soc. C, 1969, 1084 DOI: 10.1039/J39690001084

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