Rearrangement on borohydride reduction of a nitrophenoxy-ester
Abstract
Reduction of ethyl-2-methyl-2-(4-nitrophenoxy)-propionate (3a) with lithium borohydride in diglyme led to rearrangement to give the nitrophenoxy-alcohol (8); the unrearranged nitrophenoxy-alcohol (4) was produced by diborane reduction of the acid (3b).