Nucleosides derived from 3- and 4-deoxy-D-xylo-hexose
Abstract
Three methods for the preparation of 4-deoxy-D-xylo-hexose have been studied. A series of nucleosides containing the 3- or 4-deoxy-D-xylo-hexosyl group has been synthesised. The configuration of these compounds has been investigated by nuclear magnetic resonance and optical rotatory dispersion measurements. A report on the biological evaluation of some of the compounds is included.