Cyclitols. Part XXII. Synthesis of some mannosyl- and mannosylmannosyl-myoinositols, and of galactinol

Abstract

Two diastereoisomeric α-D-mannopyranosylmyoinositols have been synthesised in poor yield from (±)-1,4,5,6-tetra-O-acetylmyoinositol by the Königs–Knorr reaction. Each compound was then converted into the 1 → 6-linked mannosylmannosyl derivative. Galactinol [1-O-α-D-galactopyranosyl-(1R)-myoinositol] was synthesised in a similar way. Acid reversion of mannose gives mainly α-(1 → 6)-linked oligosaccharides.