Our Emerging Investigator Series features exceptional work by early-career researchers working in the field of materials science.
Read Ankan Dutta Chowdhury’s Emerging Investigator Series article ‘Cu 3 N–Fe nanocube-based electrochemical sensing of cancer metabolites with minute-scale response time’ ( https://doi.org/10.1039/D5MH01603G ) and read more about him in the interview below:
MH: Your recent Materials Horizons Communication describes an electrochemical biosensor using iron-doped copper nitride (Cu 3 N–Fe) nanostructures for the rapid detection of hydrogen peroxide (H 2 O 2 ), a key metabolic biomarker released by cancer cells. How has your research evolved from your first article to this most recent article and where do you see your research going in future?
AC: My research journey has evolved from fundamental nanomaterial design toward translational biosensing and diagnostic platforms. During my early PhD and postdoctoral work, I primarily focused on developing nanostructured interfaces, such as graphene quantum dots, magnetic nanocomposites, and plasmonic assemblies for sensitive electrochemical and optical detection of biomolecules and pathogens. These studies helped to establish principles for signal amplification, surface functionalisation, and bio to nano interactions. Over time, my research has moved toward multifunctional and application-driven nanoplatforms, particularly for real-time disease diagnostics. The current Materials Horizons work on Cu3N–Fe nanocubes represents a natural progression, where we combine controlled nanocrystal engineering, metal doping, and electrocatalytic activity to directly sense human body-associated metabolites in rapid response times. This study bridges fundamental materials chemistry with clinically relevant bioanalysis, showing how controlled compositional tuning can significantly enhance sensing performance. Looking ahead, my group aims to expand this concept into integrated and portable diagnostic systems by coupling metal-doped Cu3N nanostructures with disposable electrodes and point-of-care devices. We are also interested in combining sensing with therapeutic or regulatory functions, such as integrating biosensing with targeted drug or siRNA delivery, thereby moving toward true theranostic nanoplatforms for cancer, infectious diseases, and food safety applications.
MH: In your opinion, what are the most important questions to be asked/answered in this field of research?
AC: Some of the most important questions involve how to reliably translate high-performance nanomaterial-based sensors from the laboratory to real clinical or field settings, and how to ensure reproducibility, robustness, and long-term stability. Another key question is how to integrate multifunctional nanomaterials into various applications such as sensing, imaging, and therapy into a single nanoplatform without compromising simplicity or cost-effectiveness. Addressing scalability, user-friendliness, and regulatory considerations will be crucial for real-world impact.
MH: What do you find most challenging about your research?
AC: Working at the interface of materials science, chemistry, biology, and engineering is both exciting and challenging. One major challenge is achieving consistent performance when moving from controlled laboratory conditions to complex biological or environmental samples. Additionally, as an early to mid-career researcher, balancing funding acquisition, administrative responsibilities, mentoring students, and maintaining research momentum is demanding. Access to advanced characterisation facilities and interdisciplinary collaboration is also essential and sometimes limiting.
MH: In which upcoming conferences or events may our readers meet you?
AC: I regularly participate in national and international conferences related to nanotechnology, biosensors, and analytical chemistry. Readers may meet me at conferences organised by the American Chemical Society (ACS), and Materials Research Society (MRS), as well as interdisciplinary meetings focused on biosensing, diagnostics, and nanomedicine. I also actively engage in academic seminars and collaborative meetings within India and abroad.
MH: How do you spend your spare time?
AC: Whenever possible, I enjoy spending quality time with my family and friends, which helps me maintain balance and perspective. I also like reading, playing games and meeting people and occasionally watching movies or music. These activities help me refresh and return to research with renewed enthusiasm.
MH: Can you share one piece of career-related advice or wisdom with other early career scientists?
AC: My advice to early career scientists is to remain curious, persistent, and patient. Building a research career takes time, and setbacks are inevitable. Focusing on strong fundamentals, maintaining scientific integrity, and developing interdisciplinary skills can make a significant difference. Most importantly, try to find science in everything.
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