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Correction: The effect of cyclic fluid perfusion on the proinflammatory tissue environment in osteoarthritis using equine joint-on-a-chip models

Johannes Heidenbergera, Eva I. Reihsab, Jonathan Straussab, Martin Frauenlobb, Sinan Gültekinc, Iris Gernerc, Stefan Toegelad, Peter Ertlb, Reinhard Windhagera, Florien Jennerc and Mario Rothbauer*ab
aDepartment of Orthopedics and Trauma Surgery, Karl Chiari Lab for Orthopaedic Biology, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090 Vienna, Austria. E-mail: mario.rothbauer@muv.ac.at
bFaculty of Technical Chemistry, Technische Universität Wien, Getreidemarkt 9/163, 1060 Vienna, Austria. E-mail: mario.rothbauer@tuwien.ac.at
cDepartment for Small Animals and Horses, Centre for Equine Health and Research, Equine Surgery Unit, Veterinary Regenerative Medicine Laboratory, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210 Vienna, Austria
dLudwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria

Received 29th April 2025 , Accepted 29th April 2025

First published on 9th May 2025


Abstract

Correction for ‘The effect of cyclic fluid perfusion on the proinflammatory tissue environment in osteoarthritis using equine joint-on-a-chip models’ by Johannes Heidenberger et al., Lab Chip, 2025, 25, 2256–2269, https://doi.org/10.1039/d4lc01078g.


The authors sincerely apologise for the incorrect duplication of Fig. 6A in the position of Fig. 8A. The corrected version of Fig. 8 is supplied here.
image file: d5lc90048d-f8.tif
Fig. 8 Effect fluid flow on inflamed mono- and cocultures of chondrocytes and synoviocytes. (A) Gene expression levels of perfused and IL-1β-treated chondrocytes and synoviocyte biochip mono- and cocultures at day 10 post-seeding for MMP1 and IL6. The data is expressed as relative expression (fold change) to the housekeeping gene SDHA with n = 3–5 biological replicates (Mann–Whitney test, *p < 0.05). (B) Extended gene expression panel of fluid mechanically actuated IL-1β-treated chondrocyte biochip mono- and cocultures for SOX9, RUNX2, COL10A1, SPARC, SPP1, COX2 and COMP genes. The data is expressed as relative expression (fold change) to the housekeeping gene SDHA with n = 3–5 biological replicates (Mann–Whitney test, *p < 0.05).

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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