Tag-Laser Induced Breakdown Spectroscopy (Tag-LIBS): Progress and Prospects
(Note: The full text of this document is currently only available in the PDF Version )
Ali Safi and Noureddine Melikechi
First published on 10th September 2025
Abstract
Tag-Laser Induced Breakdown Spectroscopy (Tag-LIBS) is an emerging technique designed to enhance the analytical performance of conventional LIBS using specific tagging strategies. This review of Tag-LIBS presents studies on its applications since its introduction in 2009. We describe the methodology of Tag-LIBS, with a focus on the types of tags used, the mechanisms behind tagging, and the approaches used to achieve molecular or elemental specificity. In addition, we review common assay types and techniques for separation and enrichment that enhance both sensitivity and selectivity. Applications of Tag-LIBS in biomedical and environmental science are highlighted, followed by an analysis of its capabilities compared to other bioassay techniques, considering metrics beyond the conventional Limit of Detection (LOD).