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Expression of concern: Microchip-based structure determination of low-molecular weight proteins using cryo-electron microscopy

Michael A. Casasanta ab, G. M. Jonaid ac, Liam Kaylor ad, William Y. Luqiu be, Maria J. Solares ad, Mariah L. Schroen b, William J. Dearnaley ab, Jarad Wilson f, Madeline J. Dukes g and Deborah F. Kelly *ab
aDepartment of Biomedical Engineering, Pennsylvania State University, University Park, PA 16802, USA. E-mail: Debkelly@psu.edu
bMaterials Research Institute, Pennsylvania State University, University Park, PA 16802, USA
cBioinformatics and Genomics Graduate Program, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
dMolecular, Cellular, and Integrative Biosciences Graduate Program, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
eDepartment of Electrical and Computer Engineering, Duke University, Durham, NC 27708, USA
fRayBiotech Life, Peachtree Corners, GA 30092, USA
gApplications Science, Protochips, Inc., Morrisville, NC 27560, USA

Received 8th February 2024 , Accepted 8th February 2024

First published on 14th February 2024


Abstract

Expression of concern for ‘Microchip-based structure determination of low-molecular weight proteins using cryo-electron microscopy’ by Michael A. Casasanta et al., Nanoscale, 2021, 13, 7285–7293, https://doi.org/10.1039/D1NR00388G.


The Royal Society of Chemistry is publishing this expression of concern in order to alert readers that concerns have been raised regarding the accuracy of some of the single particle data for N protein specimens presented in this article. An investigation is underway, and an expression of concern will continue to be associated with the article until a final outcome is reached.

 

Signed: Heather Montgomery, Managing Editor, Nanoscale

Date: 25 January 2024


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