Open Access Article
This Open Access Article is licensed under a Creative Commons Attribution 3.0 Unported Licence
Retraction: PEG-poly(amino acid)s/EpCAM aptamer multifunctional nanoparticles arrest the growth and metastasis of colorectal cancer
Yingru
Zhang
ab,
Chunpu
Li
a,
Ru
Jia
a,
Ruixuan
Gao
c,
Yiyang
Zhao
ab,
Qing
Ji
a,
Jianfeng
Cai
*c,
Qi
Li
*ab and
Yan
Wang
*ab
aDepartment of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. E-mail: wangyan_sg@126.com; yanwang@shutcm.edu.cn
bAcademy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. E-mail: qili@shutcm.edu.cn
cDepartment of Chemistry, University of South Florida, 4202 E. Fowler Avenue, Tampa, FL 33620, USA. E-mail: jianfengcai@usf.edu
First published on 14th October 2024
Abstract
Retraction of ‘PEG-poly(amino acid)s/EpCAM aptamer multifunctional nanoparticles arrest the growth and metastasis of colorectal cancer’ by Yingru Zhang et al., Biomater. Sci., 2021, 9, 3705–3717, https://doi.org/10.1039/D1BM00160D.
The Royal Society of Chemistry hereby wholly retracts this Biomaterials Science article due to concerns with the reliability of the data.
In Fig. 5b, the EpCAM-TSIIA-NPs 32 h image is identical to an image in another paper by the authors,1 specifically the intestinal BL1 mouse in Fig. 8a and the top left mouse image in Fig. 8b (intestinal FITC-GE11-Evo-NPs BLI 1 h) of ref. 1.
In Fig. 6E, the EpCAM-TSIIA-NPs image overlaps with an image in another paper by the authors,1 specifically the Ge11-Evo-NPs image in Fig. 6A of ref. 1.
An independent expert has raised concerns regarding the accuracy of the error bars and the authors have not been able to address this.
Given the number and significance of the concerns about the validity of the data, the findings presented in this paper are no longer reliable.
The authors were informed about the retraction of the article. Jianfeng Cai has agreed with the decision, and the other authors have not responded.
Signed: Jianfeng Cai
Date: 3rd October 2024
Retraction endorsed by Maria Southall, Executive Editor, Biomaterials Science
References
1 C. Li, G. Cai, D. Song, R. Gao, P. Teng, L. Zhou, Q. Ji, H. Sui, J. Cai, Q. Li and Y. Wang, Biomater. Sci., 2019, 7, 3627–3639, DOI: 10.1039/C9BM00613C.
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