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Correction: The influence of chirality on the behavior of oligonucleotides inside cells: revealing the potent cytotoxicity of G-rich L-RNA

Chen-Hsu Yu and Jonathan T. Sczepanski *
Department of Chemistry, Texas A&M University, College Station, Texas 77843, USA. E-mail: jon.sczepanski@chem.tamu.edu

Received 15th June 2023 , Accepted 15th June 2023

First published on 23rd June 2023


Abstract

Correction for ‘The influence of chirality on the behavior of oligonucleotides inside cells: revealing the potent cytotoxicity of G-rich L-RNA’ by Chen-Hsu Yu et al., Chem. Sci., 2023, 14, 1145–1154, https://doi.org/10.1039/D2SC05511B.


The originally published version of this manuscript contained an incorrect figure for Fig. 3. The original Fig. 3 showed a toxicity time-course for D-Me(GGAA)8 compared to L-r(GGAA)8 when the intended graphic should have shown a toxicity time-course for hairpin L-r(GC/GC) compared to L-r(GGAA)8. The correct version of Fig. 3 is as follows, and replaces that within the original manuscript.
image file: d3sc90119j-f3.tif
Fig. 1 Time-dependent viability assay (CCK-8) of HeLa cells treated with 200 nM of L-r(GC/GC) hairpin. L-r(GGAA)8 is shown for reference. Data are mean ± S.D. (n = 3 biological replicates).

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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